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Immunosuppressive Drugs


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Description

Immunosuppression is the body's ability to set itself free from diseases and other infection. This suppression may happen because of a disease which targets the immune system, for instance, HIV and cancer. In some cases, the doctor might include Immunosuppression deliberately. This could be necessary after organ or tissue transplantation. This reduces the chances of organ rejection.

 

Symptoms and signs

The need for immunosuppression drugs after surgery can be predicted through the following signs and symptoms:

  • Regular fever above 100 degrees
  • Blood in the urine
  • Infection or inflammation of the internal organs
  • Sinus infection
  • Diarrhea
  • Pneumonia
  • Pinkeye
  • Colds
  • Sudden weight gain
  • Sun sensitivity
  • Patchy hair loss
  • Pain in the joints
  • Rashes
  • Headaches
  • Yellow skin and eyes

 

If found with these symptoms after a surgery, it is recommended to consult with the doctor right away.

 

Causes

Immunodeficiency is the sign that the immune system of the body is functioning poorly. A drop in the immune system can lead to significant consequences. Either someone is born with immunodeficiency, or it happened when an infection attacked the body.

Primary immunodeficiency causes are:

  • XLA- X-linked agammaglobulinemia
  • CVID- common variable immunodeficiency
  • SCID- Severe combined immunodeficiency
  • Secondary immunodeficiency causes
  • Chemotherapy
  • Radiation
  • Severe burns
  • Malnutrition
  • Diabetes

 

Common Drugs

  • Cytotoxic drugs
  • Cyclosporine
  • Azathioprine
  • Chlorambucil
  • Leflunomide
  • Mycophenolate mofetil

 

Prevention

The primary immunodeficiency can't be prevented entirely. Although it can be controlled. However, secondary immunodeficiency has many preventions. For instance, immunodeficiency caused by AIDS can be prevented by not indulging into unprotected sex.

To keep the immune system healthy, one must get at least eight hours of sound sleep. Also, if someone is diagnosed with immunodeficiency, stay from sick people.

 

Diagnosis

Once the doctor suspects that a patient is suffering from immunodeficiency, follow these steps.

  • The physician will conduct a physical test of the whole body
  • Ask about family's medical history
  • Conduct a blood sample test to identify the white blood cell count
  • Conduct a blood sample test for T cell count
  • Check immunoglobulin levels.

 

FAQs

How can immunodeficiency disorder be treated?

The treatment for immunodeficiency disorder will depend on how severe the case is. If someone has AIDS, then the doctor might prescribe relevant immunosuppressive drugs. Someone who has it after chemotherapy might be asked to go for immunosuppressive therapy. The primary treatment for immunodeficiency disorder is mostly therapy and antibiotics.

 

When to contact a doctor?

If someone has a fever over 100 °F, then visit a doctor right away. People going through chemotherapy should consult a doctor if there are any signs of immunodeficiency diseases. Also, if there is a family history, it is better to go to a doctor as soon as possible.

 

What are the possible complications of immunodeficiency disorder?

If diagnosed with an immunodeficiency disorder, then the following complications may occur:

  • Increased chances of infection
  • Increased risk of tumors and cancer cells
  • Getting ill frequently

 

Can primary immunodeficiency disorder be cured?

Unfortunately, there is no permanent cure for immunodeficiency disorder. However, the doctor may keep the children healthy by giving them anti-rejection drugs.